Developmental Toxicity of Inhaled Methyl Ethyl Ketone in Swiss Mice

Methyl ethyl ketone peroxide

Methyl ethyl ketone and methyl isobutyl ketone not carcinogenic.

Methyl Ethyl Ketone and Methyl Isobutyl Ketone Not Carcinogenic The April 22, 1993, issue of Environmental Health Perspectives contained a commentary by Legator and Strawn entitled "Public Health Policies Regarding Hazardous Waste Sites and Cigarette Smoking: An Argument by Analogy." Although the article does not include any discussion of either methyl ethyl ketone (MEK) or methyl isobutyl keto...

Methyl isocyanate: reproductive and developmental toxicology studies in Swiss mice.

Studies were conducted in Swiss (CD-1) mice to evaluate the potential of inhaled vapors of methyl isocyanate (MIC) to affect reproduction and development. Inhaled MIC at concentrations of 0, 1, or 3 ppm, 6 hr per day during days 14 through 17 of gestation caused a significant increase in the number of dead fetuses at birth and caused a significant decrease in neonatal survival during lactation....

Thermal Hazard Analysis of Methyl Ethyl Ketone Peroxide

In the past forty years in Japan and Taiwan, many thermal explosions have been caused by methyl ethyl ketone peroxide (MEKPO) under the influence of external fire and others. Thermograms of commercialized MEKPO dimers were first screened by Differential Scanning Calorimetry (DSC) to determine the heat of decomposition and exothermic onset temperature. Thermal runaway phenomena were then thoroug...

Short-term toxicity of methyl amyl ketone in rats.

Abstract--Methyl amyl ketone was given to rats, by oral intubation in oil solution, at dose levels of 0 (control), 20, 100 or 500 mg/kg/day for 13 wk. There were no statistically significant differences between treated and control rats in the rate of body-weight gain, food or water consumption, haematological findings, or the results of renal concentration tests. The histological appearance of ...